Actives and Speciality Compounds

News

Safe handling of fibre drums in API production from Weiss GWE at ACHEMA 2012– 2-May-2012

German firm adds WIBO drum port to barrier system

Contained API particle size reduction facility gives flexible operation– 12-Mar-2012

Hosokawa equipment is suitable for milling down to ultrafine particles

PolyOne and Sanitized collaborate to inhibit bacteria– 1-Dec-2011

Will provide medical device polymers with antimicrobial technology

LIVE FROM CPhI: SAFC Verona facility receives SafeBridge Certification– 25-Oct-2011

Certification of new HPAPI plant reflects company's ongoing commitment to safety

Almac to boost manufacturing capacity at Craigavon– 24-Oct-2011

Invests in new reactor vessels and cleanroom product isolation and drying equipment

Researchers develop antimicrobial workwear that is comfortable to wear– 3-Oct-2011

Based on regenerated cellulose fibres with a zinc antimicrobial coating

PSL to supply FilterBoxes to new Helsinn facility– 8-Sep-2011

The trend towards increasingly potent products will cause production, cleaning and safety issues

Nitric oxide is better at blocking E.coli growth than silver– 18-Aug-2011

Does not have the drug resistance issues of antibiotics, study finds

BD to purchase Carmel Pharma– 28-Jul-2011

Will expand healthcare worker safety offerings to include reducing exposure to hazardous drugs

Lonza to expand cytotoxic manufacturing capabilities– 12-May-2011

Multi-kg production planned to serve growing oncology API market

Helsinn to build €15.4m cytotoxic plant in Switzerland– 3-Mar-2011

Will start commissioning laboratory projects in 2012

Syntopix to research biofilms for Beiersdorf– 18-Jan-2011

To develop and validate screening assays to improve topical antimicrobial efficacy

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Articles

A green building for potent drugs– 21-Dec-2011

Pfizer CentreSource uses the high potency suites at Pfizer's Freiburg, Germany plant to offer an end to end third party contract manufacturing service for high potency drugs. The high potency area offers dry compaction, wet granulation, bead coating, melt extrusion, external lubrication and compression scale-up

What’s in a seal?– 23-Aug-2010

As API potency levels continue to increase, so too does the need for co-operation between equipment maker and seal manufacturer. Elastomer maker Precision Polymer Engineering and ChargePoint Technology explain how the optimum elastomer was selected for a split butterfly valve

Contained but not constrained– 20-May-2010

Highly potent drugs require specialised manufacturing facilities to ensure they do not escape into the environment. SAFC’s Trevor Calkins describes how the company designed its multipurpose manufacturing plants to meet the complex containment requirements

Handling potent drug materials– 16-Apr-2010

Drug manufacturer Hovione has opened a new spray drying facility in Loures, Portugal, for potent active ingredients. Marco Marques, head of production, describes the safety protocols

Winning designs– 22-Feb-2010

Several innovative contamination control systems featured in the pharmaceutical facilities recognised for their design and efficiency in the International Society for Pharmaceutical Engineering Facility of the Year awards. Susan Birks takes a look inside

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